Adventitial Biology
نویسندگان
چکیده
منابع مشابه
Adventitial Fibroblast Heterogeneity
vascular function and structure from the “outside-in.” The purpose of this review is to provide evidence that, in response to injury, resident adventitial fibroblasts can be activated to exhibit different functional characteristics that contribute significantly to pulmonary vascular remodeling. Data will be presented supporting the concept that fibroblasts (in some cases only specific subpopula...
متن کاملAdventitial ablation technique that permits the assessment of adventitial-dependent contribution to microvascular contractile function.
Resistance arteries have been implicated as a major contributing factor in the sequela of disease conditions such as hypertension and diabetes and, as such, are a major focus of cardiovascular research. The paracrine influence of the intimal endothelial layer of resistance arteries is well established. Considering the growing body of evidence substantiating a functionally relevant vascular adve...
متن کاملEndothelin-1 expression in vascular adventitial fibroblasts.
Endothelial cells are a major source of endothelin (ET)-1, but the possibility that vascular adventitial fibroblasts generate ET-1 has not been explored. We hypothesized that aortic adventitial fibroblasts have the ability to produce ET-1, which may contribute to extracellular matrix synthesis. Vascular adventitial fibroblasts were isolated from mouse aorta and incubated with various concentrat...
متن کاملTracking Adventitial Fibroblast Contribution to Disease
The dynamic functions of the adventitia are a recent interest to vascular biology. Constituents of the adventitia contribute to neointimal hyperplasia, extracellular matrix (ECM) production and deposition, vessel size regulation, and immune cell recruitment. Previous studies mainly relied on in vitro cell culture to understand how these cells respond to pathological conditions. Although informa...
متن کاملTracking Adventitial Fibroblast Contribution to Disease
The dynamic functions of the adventitia are a recent interest to vascular biology. Constituents of the adventitia contribute to neointimal hyperplasia, extracellular matrix (ECM) production and deposition, vessel size regulation, and immune cell recruitment. Previous studies mainly relied on in vitro cell culture to understand how these cells respond to pathological conditions. Although informa...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2011
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.110.221176